Enteropathogen Resource Integration Center (ERIC)

ERIC BRC logo

You may have reached this page while looking for the Enteropathogen Resource Integration Center (ERIC) BRC at www.ericbrc.org. The Bioinformatics Resource Centers (BRCs) for Infectious Diseases program is a continuation and expansion of a program initiated in 2004 and consists of four new centers, each specializing in a different group of pathogens. The PATRIC BRC is now responsible for all bacterial species in the NIAID Category A-C Priority Pathogen lists for biodefense research, and pathogens causing emerging/reemerging infectious diseases.

For ERIC users, we understand that the resource was valuable to your work. As such, we will be doing our very best to create a useful PATRIC resource to continue supporting your work. We realize that the transition will cause disruptions. However, it is a priority for us to work with established BRC users and communities to identify and prioritize our transition efforts. We will have a survey online soon to help us identify your needs, but in the meantime, you may contact us at patric@vbi.vt.edu with questions and requests.

We have concentrated on the transfer of genomic data for this initial release. We anticipate adding new data, tools, and website features over the next several months. We look forward to working with you during the next 5 years.

List of Genera

Genus name Genomes from BRC Link Description
Escherichia 37 Taxonomy Overview Genome List Feature Table Escherichia, a genus of gram-negative rod-shaped bacteria, belongs to the family Enterobacteriaceae. Escherichia coli has become a model organism for studying many of life's essential processes partly due to its rapid growth rate and simple nutritional requirements. Normally E. coli serves a useful function in the body by suppressing the growth of harmful bacterial species and by synthesizing appreciable amounts of vitamins. A minority of E. coli strains are capable of causing human illness by several different mechanisms. E. coli serotype O157:H7 is a rare variety of E. coli that produces large quantities of one or more related, potent toxins that cause severe damage to the lining of the intestine.
Salmonella 29 Taxonomy Overview Genome List Feature Table Salmonella is a genus of rod-shaped, gram-negative bacteria in the family Enterobacteriaceae. This genus has two species: S. enterica, which is subdivided into over 2,000 serovars, and S. bongori. Some serovars of S. enterica, such as S. typhi, cause systemic infections and typhoid fever. Others, like S. typhimurium, cause gastroenteritis.
Shigella 9 Taxonomy Overview Genome List Feature Table Shigella is a group of gram-negative, facultative intracellular pathogens in the family Enterobacteriaceae. Recognized as the etiologic agents of bacillary dysentery or shigellosis in the 1890s, Shigella was adopted as a genus in the 1950s and subgrouped into four species: S. dysenteriae, S. flexneri, S.boydii and S. sonnei(also designated as serogroups A to D).
Yersinia 25 Taxonomy Overview Genome List Feature Table Yersinia, a gram-negative rod-shaped bacterium, is a genus of bacteria in the family Enterobacteriaceae. Yersinia pestis, the causative agent of plague, whose most common clinical form is acute febrile lymphadenitis, is more commonly known as bubonic plague. Other members of the genus, Y. entercolitica and Y. pseudotuberculosis, are also human pahtogens.
Citrobacter 1 Taxonomy Overview Genome List Feature Table Citrobacter is a genus of gram-negative coliform bacteria in the Enterobacteriaceae family and the phylum Proteobacteria. Three members of the genus, C. amalonaticus, C. diversus and C. freundii are linked to human disease with C. diversus linked to frequent nosocomial outbreaks of neonatal meningitis.
Cronobacter 1 Taxonomy Overview Genome List Feature Table Cronobacter, a genus of gram-negative, rod-shaped bacteria in the family Enterobacteriaceae and the phylum Proteobacteria, is recognised as causative agents of neonatal bacteraemia, meningitis and necrotising enterocolitis.
Enterobacter 1 Taxonomy Overview Genome List Feature Table Some members of the genus Enterobacter are important nosocomial pathogens. Several strains of these gram-negative rod-shaped bacteria in the family Enterobacteriaceae cause opportunistic infections in immunocompromised patients. Two clinically-important species from this genus are E. aerogenes and E. cloacae.
Erwinia 2 Taxonomy Overview Genome List Feature Table Current members of the genus Erwinia are primarily pathogens of plants. They are gram-negative rod-shaped bacteria in the family Enterobacteriaceae. The genus was named for the first phytobacteriologist, Erwin Smith.
Klebsiella 2 Taxonomy Overview Genome List Feature Table Klebsiella is a genus of non-motile, gram-negative, rod shaped bacteria in the family Enterobacteriaceae with a prominent polysaccharide-based capsule. Three species in the genus Klebsiella are associated with illness in humans: K. pneumoniae is a primary pathogen capable of causing urinary tract infections and pneumonia in otherwise healthy people, K. oxytoca can cause a variety of nosocomial infections, and K. granulomatis causes chronic genital ulcerative disease.
Pectobacterium 1 Taxonomy Overview Genome List Feature Table Pectobacterium are gram-negative rod-shaped bacterium in the family Enterobacteriaceae that are pathogens of angiosperms with a broad host range. Pectobacterium carotovorum (syn Erwinia carotovora) is a plant pathogen able to cause disease in almost any plant tissue it invades.
Photorhabdus 1 Taxonomy Overview Genome List Feature Table Photorhabdus is a gram-negative member of the family Enterobacteriaceae that lives in a mutualistic association with a Heterorhabditis nematode worm. The nematode worm burrows into insect prey and regurgitates Photorhabdus, which goes on to kill the insect. Once the insect host is dead the bacteria bioconvert the tissues into more bacteria. The nematode feeds off the growing bacteria until the insect tissues are exhausted, whereupon they reassociate and leave the cadaver in search of new prey. This highly efficient partnership has been used for many years as a biological crop protection agent. In addition to its well-described role as an insect pathogen one species of the genus, P. asymbiotica, causes infection in otherwise healthy humans.
Proteus 1 Taxonomy Overview Genome List Feature Table Proteus is a gram-negative member of the family Enterobacteriaceae. Several species in this genus are opportunistic human pathogens. Most prominent is P. mirabilis which causes wound and urinary tract infections. Another species, P. vulgaris, can cause urinary tract and wound infections and is a common cause of sinus and respiratory infections.
Serratia 1 Taxonomy Overview Genome List Feature Table Serratia is a genus of gram-negative, facultatively anaerobic, rod-shaped bacteria of the Enterobacteriaceae family. Serratia marcescens is the primary pathogenic species and is commonly found in the respiratory and urinary tracts of hospitalized adults and in the gastrointestinal system of children. Rare reports have described disease resulting from infection with S. plymuthica, S.liquefaciens, S. rubidaea, S. odorifera and S. fonticola.