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National Microbial Pathogen Data Resource (NMPDR)

NMPDR BRC logo

You may have reached this page while looking for the National Microbial Pathogen Data Resource (NMPDR) BRC at www.nmpdr.org. The Bioinformatics Resource Centers (BRCs) for Infectious Diseases program is a continuation and expansion of a program initiated in 2004 and consists of four new centers, each specializing in a different group of pathogens. The PATRIC BRC is now responsible for all bacterial species in the NIAID Category A-C Priority Pathogen lists for biodefense research, and pathogens causing emerging/reemerging infectious diseases.

For NMPDR users, we understand that the resource was valuable to your work. As such, we will be doing our very best to create a useful PATRIC resource to continue supporting your work. We realize that the transition will cause disruptions. However, it is a priority for us to work with established BRC users and communities to identify and prioritize our transition efforts. We will have a survey online soon to help us identify your needs, but in the meantime, you may contact us at patric@vbi.vt.edu with questions and requests.

We have concentrated on the transfer of genomic data for this initial release. We anticipate adding new data, tools, and website features over the next several months. We look forward to working with you during the next 5 years.

List of Genera

Genus name Genomes from BRC Link Description
Campylobacter 12 Taxonomy Overview Genome List Feature Table The genus Campylobacter, meaning 'twisted bacteria', describes gram-negative bacteria that are members of the order Campylobacterales in the class Epsilonproteobacteria. At least a dozen species of Campylobacter have been implicated in human disease with C. jejuni and C. coli the most common. Campylobacter jejuni is now recognized as one of the main causes of bacterial foodborne disease in many developed countries.
Chlamydia 1 Taxonomy Overview Genome List Feature Table The order Chlmydiales contians only one family, the Chlamydiaceae, and one genus, Chlamydia. Chlamydiae are obligate intracellular bacteria and four species are currently recognized, C. pecorum, C. psittaci, C. trachomatis and C. pneumoniae. All except C. pecorum have been associated with human disease.
Chlamydophila 5 Taxonomy Overview Genome List Feature Table Chlamydophila is a bacterial genus belonging to the family Chlamydiaceae, order Chlamydiales, class/phylum Chlamydiae. Several species within this genus cause disease in humans, most notably C. pneumoniae and C. psittaci. Chlamydophila pneumoniae infects humans and is a major cause of pneumonia. Chlamydophila psittaci causes endemic avian chlamydiosis, epizootic outbreaks in mammals, and respiratory psittacosis in humans.
Haemophilus 8 Taxonomy Overview Genome List Feature Table Haemophilus is a genus of gram-negative, pleomorphic, coccobacilli bacteria belonging to the Pasteurellaceae family of the class Gammaproteobacteria. The genus includes commensal organisms along with some significant pathogenic species such as H. influenzae, a cause of sepsis and bacterial meningitis in young children, and H. ducreyi, the causative agent of chancroid. All members are either aerobic or facultatively anaerobic.
Listeria 19 Taxonomy Overview Genome List Feature Table Species of the genus Lister are gram-positive bacilli that belong to the family Listeriaceae in the order Bacilli. There are six species of Listeria. Only L. monocytogenes is pathogenic for humans causing listerosis, an uncommon but serious zoonotic infection contracted by eating contaminated food.
Mycoplasma 12 Taxonomy Overview Genome List Feature Table Mycoplasma is one of several genera within the Mollicutes in the phylum Tenericutes, a class of bacteria that have small genomes and lack a cell wall. Several species are pathogenic in humans, including M. pneumoniae, which is an important cause of atypical pneumonia and other respiratory disorders, and M. genitalium, which is believed to be involved in pelvic inflammatory diseases.
Neisseria 5 Taxonomy Overview Genome List Feature Table Neisseria is a genus of the epsilon group phylum Proteobacteria and are gram-negative diplococci that resemble coffee beans when viewed microscopically. They are a large family of commensal bacteria that colonize the mucosal surfaces of many animals. Only two of the eleven species that colonize humans are pathogens, N. meningitidis and N. gonorrhoeae.
Staphylococcus 18 Taxonomy Overview Genome List Feature Table Staphylococcus, a spherical gram-positive bacteria that is immobile and forms grape-like clusters, is a member of the phylum Firmicutes. Most of the species within this genus are nonpathogenic. A notable exception is S. aureus, the most common cause of staph infections.
Streptococcus 34 Taxonomy Overview Genome List Feature Table Streptococcus is a genus of spherical gram-positive bacteria belonging to the phylum Firmicutes. Among its pathogenic members are S. pyogenes, the cause of many important human diseases ranging from mild superficial skin infections to life-threatening systemic diseases, and S. pneumoniae, the most common cause of bacterial meningitis in adults and children.
Treponema 2 Taxonomy Overview Genome List Feature Table Treponema is a member of the phylum Spirochaetes. Treponema pallidum is a motile spirochaete that is generally acquired by close sexual contact and can also be transmitted to a fetus during the later stages of pregnancy, giving rise to congenital syphilis.
Ureaplasma 13 Taxonomy Overview Genome List Feature Table Ureaplasma is one of several genera within the class Mollicutes of the phylum Tenericutes. There are six recognized Ureaplasma species. Ureaplasma urealyticum is part of the normal genital flora and is found in about 70% of sexually active humans. It can also cause disease, including non-specific urethritis, infertility, chorioamnioitis, stillbirth, premature birth, and in the perinatal period, pneumonia or meningitis.
Vibrio 24 Taxonomy Overview Genome List Feature Table Vibrio is a genus of gram-negative rod-shaped bacteria in the class Gammaproteobacteria and phylum Proteobacteria. The genus Vibrio contains many pathogenic members, the most famous being Vibrio cholerae, a historically feared epidemic diarrheal disease.